>>> import pandas
>>> # create three rows of [0, 1, 2]
>>> df = pandas.DataFrame([range(3), range(3), range(3)])
>>> print df
   0  1  2
0  0  1  2
1  0  1  2
2  0  1  2
>>> my_columns = ["a", "b", "c"]
>>> df.columns = my_columns
>>> print df
   a  b  c
0  0  1  2
1  0  1  2
2  0  1  2