string sql1 = "BEGIN update Table1 set name = 'joe' where id = 10;",
       sql2 = "update Table2 set country = 'usa' where region = 'americas';",
       sql3 = "update Table3 set weather = 'sunny' where state = 'CA';",
       sql4 = "update Table4 set engine = 'v8' where maker = 'benz'; END;";

string sql = string.Format("{0}{1}{2}{3}",sql1,sql2,sql3,sql4);

using (OracleConnection conn = new OracleConnection())
using (OracleCommand cmdUpdate = new OracleCommand(sql, conn))
{
    conn.Open();
    recs = cmdUpdate.ExecuteNonQuery();
}