public static readonly List ImageExtensions = new List { ".JPG", ".JPE", ".BMP", ".GIF", ".PNG" };

private void button_Click(object sender, RoutedEventArgs e)
{
    var folder = Environment.GetFolderPath(Environment.SpecialFolder.Desktop);
    var files = Directory.GetFiles(folder);
    foreach(var f in files)
    {
        if (ImageExtensions.Contains(Path.GetExtension(f).ToUpperInvariant()))
        {
            // process imagek
        }
    }
}