/etc/php5.5-sp/conf.d/opcache.ini
/etc/php5.6-sp/conf.d/opcache.ini
/etc/php7.0-sp/conf.d/opcache.ini
/etc/php7.1-sp/conf.d/opcache.ini
/etc/php7.2-sp/conf.d/opcache.ini
/etc/php7.3-sp/conf.d/opcache.ini
/etc/php7.4-sp/conf.d/opcache.ini

opcache.enable=0
sudo service php5.5-fpm-sp restart