const
    listOfTags = [{ id: 1, label: "Hello", color: "red", sorting: 0 }, { id: 2, label: "World", color: "green", sorting: 1 }, { id: 3, label: "Hello", color: "blue", sorting: 4 }, { id: 4, label: "Sunshine", color: "yellow", sorting: 5 }, { id: 5, label: "Hello", color: "red", sorting: 6 }],
    keys = ['label', 'color'],
    filtered = listOfTags.filter(
        (s => o => 
            (k => !s.has(k) && s.add(k))
            (keys.map(k => o[k]).join('|'))
        )
        (new Set)
    );

console.log(filtered);