import pandas as pd

a = ['2015-01-01' , '2015-02-01']

df = pd.DataFrame(data={'date':['2015-01-01' , '2015-02-01', '2015-03-01' , '2015-04-01', '2015-05-01' , '2015-06-01']})

print(df)
#         date
#0  2015-01-01
#1  2015-02-01
#2  2015-03-01
#3  2015-04-01
#4  2015-05-01
#5  2015-06-01

df = df[~df['date'].isin(a)]

print(df)
#         date
#2  2015-03-01
#3  2015-04-01
#4  2015-05-01
#5  2015-06-01