# credit to Stack Overflow user in the source link
# NOTE: this is ust an example, you have to adapt the query and other stuff to your needs

import sqlite3
import json

query = """
{
    "ID": "4",
    "Name": "David",
    "Transformation": "SELECT ID || Name AS NewField FROM inputdata"
}"""

query_dict = json.loads(query)

db = sqlite3.Connection('mydb')
db.execute('create table inputdata ({} VARCHAR(100));'.format(' VARCHAR(100), '.join(query_dict.keys())))
db.execute('insert into inputdata ({}) values ("{}")'.format(','.join(query_dict.keys()),'","'.join(query_dict.values())))

r = db.execute(query_dict['Transformation'])
response = {}
response[r.description[0][0]] = r.fetchone()[0]

print(response)
>>> {'NewField': '4David'}

db.execute('drop table inputdata;')
db.close()