Spend less time clicking and more time playing.

Function                        Windows            Mac
New playlist                    Ctrl-N            Cmd-N
Cut                                Ctrl-X            Cmd-X
Copy                            Ctrl-C            Cmd-C
Copy (alternative link)            Ctrl-Alt-C        Cmd-Alt-C
Paste                            Ctrl-V            Cmd-V
Delete                            Del                Del, Backspace
Select all                        Ctrl-A            Cmd-A
Play/pause                        Space            Space
Repeat                            Ctrl-R            Cmd-R
Shuffle                            Ctrl-S            Cmd-S
Next track                        Ctrl-Right        Ctrl-Cmd-Right
Previous track                    Ctrl-Left        Ctrl-Cmd-Left
Volume up                        Ctrl-Up            Cmd-Up
Volume down                        Ctrl-Down        Cmd-Down
Mute                            Ctrl-Shift-Down    Cmd-Shift-Down
Max volume                        Ctrl-Shift-Up    Cmd-Shift-Up
Show help                        F1                Cmd-Shift-?
Filter                            Ctrl-F            Cmd-F
Enter search field                Ctrl-L            Cmd-Alt-F, Cmd-L
Go back                         Alt-Left        Cmd-Alt-Left
Go forward                         Alt-Right        Cmd-Alt-Right
Play selected row                Enter            Enter
Preferences                        Ctrl-P            Cmd-,
Log out                            Ctrl-Shift-W    Cmd-Shift-W
Quit                            Alt-F4            Cmd-Q
Undo deleted song or playlist    Ctrl-Shift-Z    Ctrl-Z