var rect1 = {x: 5, y: 5, width: 50, height: 50}
var rect2 = {x: 20, y: 10, width: 10, height: 10}

if (rect1.x < rect2.x + rect2.width &&
   rect1.x + rect1.width > rect2.x &&
   rect1.y < rect2.y + rect2.height &&
   rect1.height + rect1.y > rect2.y) {
    // collision détectée !
}